Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017092 | 0.89 | HDAC6 (0.55) | HDAC6CTNNB1WNT3AALDH1A1HPGD | |
| SCHEMBL25475159 | 0.87 | HDAC6 (0.40) | HDAC6CTNNB1WNT3AALDH1A1HPGD | |
| SCHEMBL9178130 | 0.85 | LMNA (0.52) | ALDH1A1HPGDRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL1965008 | 0.84 | KMT2A (0.53) | ALDH1A1HPGDRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL27799227 | 0.84 | NPC1 (0.50) | ALDH1A1HPGDRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL6016890 | 0.83 | CTNNB1 (0.44) | HDAC6CTNNB1WNT3AALDH1A1HPGD | |
| SCHEMBL19152221 | 0.82 | HTT (0.40) | HDAC6CTNNB1WNT3AALDH1A1HPGD | |
| SCHEMBL3254826 | 0.81 | SNCA (0.46) | HDAC6CTNNB1WNT3AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3625261 | 0.80 | SNCA (0.45) | HDAC6CTNNB1WNT3AALDH1A1HPGD | |
| SCHEMBL29491309 | 0.79 | QPCT (0.38) | HDAC6CTNNB1WNT3AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |