Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.73 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 9/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | DDX3X | O00571 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968945 | 0.88 | CSNK2A2 (0.71) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL11480689 | 0.87 | CSNK2A2 (0.83) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL18292329 | 0.82 | CSNK2A2 (0.74) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL1965704 | 0.82 | SMN1; SMN2 (0.60) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1964640 | 0.80 | SMN1; SMN2 (0.55) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL1966407 | 0.80 | CSNK2A2 (0.60) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL28782500 | 0.74 | RAB9A (0.67) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL25323087 | 0.73 | RAB9A (0.60) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL30476677 | 0.73 | RAB9A (0.60) | CSNK2A2CSNK2A1NPC1RAB9AKMT2A | |
| SCHEMBL31654008 | 0.73 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |