Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968590 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53PTGER3CSNK2A2CSNK2A1 | |
| SCHEMBL1965024 | 0.80 | CSNK2A2 (0.73) | SMN1; SMN2TP53CSNK2A2CSNK2A1NPC1 | |
| SCHEMBL1966407 | 0.79 | CSNK2A2 (0.60) | SMN1; SMN2TP53CSNK2A2CSNK2A1NPC1 | |
| SCHEMBL1964639 | 0.74 | ALDH1A1 (0.39) | PTGER3NPC1RAB9AALDH1A1RXFP1 | |
| SCHEMBL11480689 | 0.72 | CSNK2A2 (0.83) | SMN1; SMN2TP53CSNK2A2CSNK2A1NPC1 | |
| SCHEMBL1968945 | 0.72 | CSNK2A2 (0.71) | SMN1; SMN2TP53CSNK2A2CSNK2A1NPC1 | |
| SCHEMBL17318711 | 0.70 | NPC1 (0.69) | SMN1; SMN2TP53PTGER3NPC1RAB9A | |
| SCHEMBL16102177 | 0.69 | RAB9A (0.62) | SMN1; SMN2TP53PTGER3CSNK2A2CSNK2A1 | |
| SCHEMBL18292329 | 0.68 | CSNK2A2 (0.74) | SMN1; SMN2TP53CSNK2A2CSNK2A1NPC1 | |
| SCHEMBL5903383 | 0.68 | NPC1 (0.55) | SMN1; SMN2TP53CSNK2A2CSNK2A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |