Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | GLS | O94925 | 15/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13357164 | 0.83 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1HSD17B10NPC1KDM4E | |
| SCHEMBL1965024 | 0.82 | CSNK2A2 (0.73) | SMN1; SMN2ALDH1A1HSD17B10NPC1KDM4E | |
| SCHEMBL12027279 | 0.77 | GLS (0.77) | ALDH1A1NPC1RAB9AGLSMEN1 | |
| SCHEMBL28162550 | 0.76 | GLS (0.71) | SMN1; SMN2ALDH1A1HSD17B10NPC1KDM4E | |
| SCHEMBL2173981 | 0.76 | EPHX2 (0.71) | SMN1; SMN2ALDH1A1NPC1KDM4EHPGD | |
| SCHEMBL19454383 | 0.75 | GLS (1.00) | SMN1; SMN2ALDH1A1HSD17B10NPC1KDM4E | |
| SCHEMBL21501804 | 0.75 | GLS (0.70) | SMN1; SMN2ALDH1A1HSD17B10NPC1KDM4E | |
| SCHEMBL13442805 | 0.75 | S1PR1 (0.58) | SMN1; SMN2ALDH1A1HSD17B10NPC1KDM4E | |
| SCHEMBL14986984 | 0.75 | GLS (0.73) | GLS | |
| SCHEMBL7483330 | 0.74 | GLS (0.81) | SMN1; SMN2ALDH1A1HSD17B10NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |