Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21168721 | 0.90 | KMT2A (0.50) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL19638277 | 0.84 | SMN1; SMN2 (0.52) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL19638183 | 0.84 | KMT2A (0.51) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL19638110 | 0.84 | RAB9A (0.51) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL544501 | 0.83 | ADORA3 (0.68) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL19637993 | 0.81 | ADORA2A (0.65) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL24072562 | 0.80 | RAB9A (0.53) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL544732 | 0.79 | ALDH1A1 (0.62) | KMT2ARAB9AMEN1NPSR1LMNA | |
| SCHEMBL544138 | 0.76 | POLB (0.56) | KMT2ARAB9ANPSR1LMNAALDH1A1 | |
| SCHEMBL19638078 | 0.75 | KMT2A (0.50) | KMT2ARAB9AMEN1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248964-B1 | THIAZOLE MODULATORS OF A3 ADENOSINE RECEPTORS | PALOBIOFARMA SL (ES) | 2019-07-17 | — | — | EP | disclosed |
| EP-3248964-A1 | THIAZOLE MODULATORS OF A3 ADENOSINE RECEPTORS | PALOBIOFARMA S.L. (ES) | 2017-11-29 | — | — | EP | disclosed |