Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22543810 | 0.88 | DRD2 (0.47) | DRD2DRD3ABCB1MEN1TP53 | |
| SCHEMBL20889998 | 0.87 | HRH3 (0.50) | DRD2DRD3PNMTMEN1TP53 | |
| SCHEMBL21267040 | 0.84 | DRD2 (0.53) | DRD2DRD3ABCB1MEN1TP53 | |
| SCHEMBL21267041 | 0.83 | DRD2 (0.43) | DRD2DRD3ABCB1MEN1TP53 | |
| SCHEMBL19650438 | 0.83 | HRH3 (0.51) | DRD2DRD3ABCB1MEN1KMT2A | |
| SCHEMBL21267719 | 0.83 | KMT2A (0.47) | DRD2DRD3MEN1TP53ALOX15 | |
| SCHEMBL22860596 | 0.83 | DRD2 (0.49) | DRD2DRD3ABCB1MEN1TP53 | |
| SCHEMBL13255041 | 0.82 | DRD2 (0.54) | DRD2DRD3PNMTABCB1MEN1 | |
| SCHEMBL10039921 | 0.81 | MAOA (0.55) | DRD2DRD3HRH3 | |
| SCHEMBL20890474 | 0.81 | DRD2 (0.47) | DRD2DRD3ABCB1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248968-A1 | RESORCINOL DERIVATIVE AS HSP90 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2017-11-29 | — | — | EP | disclosed |