Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19650358 | 0.83 | DRD2 (0.52) | DRD2DRD3ABCB1HRH3MEN1 | |
| SCHEMBL19650438 | 0.81 | HRH3 (0.51) | DRD2DRD3ABCB1HRH3MEN1 | |
| SCHEMBL22543810 | 0.80 | DRD2 (0.47) | DRD2DRD3ABCB1HRH3MEN1 | |
| SCHEMBL20889998 | 0.79 | HRH3 (0.50) | DRD2DRD3HRH3MEN1TP53 | |
| SCHEMBL14287690 | 0.79 | HRH3 (0.61) | DRD2DRD3ABCB1HRH3HTR1A | |
| SCHEMBL21267040 | 0.77 | DRD2 (0.53) | DRD2DRD3ABCB1HRH3MEN1 | |
| SCHEMBL21267041 | 0.76 | DRD2 (0.43) | DRD2DRD3ABCB1HRH3MEN1 | |
| SCHEMBL21267719 | 0.76 | KMT2A (0.47) | DRD2DRD3HTR1AHTR2ASLC6A4 | |
| SCHEMBL10039921 | 0.75 | MAOA (0.55) | DRD2DRD3HRH3HTR2ASLC6A4 | |
| SCHEMBL25818517 | 0.74 | MEN1 (0.45) | DRD2DRD3MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003314-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-01-07 | — | — | WO | disclosed |