Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725416 | 0.86 | MEN1 (0.42) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL21725399 | 0.86 | MEN1 (0.41) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL19650645 | 0.85 | MEN1 (0.36) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL24767420 | 0.81 | MEN1 (0.36) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL19650545 | 0.81 | CYP1A1 (0.40) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL21725377 | 0.81 | MEN1 (0.43) | ADORA2AALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14725242 | 0.80 | CYP11B1 (0.50) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL22308740 | 0.79 | MEN1 (0.48) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL19650632 | 0.79 | ENPP3 (0.36) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL14725241 | 0.79 | MEN1 (0.50) | ADORA2ACYP11B1ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248966-B1 | PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO LTD (JP) | 2022-12-21 | — | — | EP | disclosed |
| EP-3248966-A1 | PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |