Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MMP2 | P08253 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MMP9 | P14780 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MMP8 | P22894 | 1/20 | 0.64 |
| ▸ | CCR1 | P32246 | 1/20 | 0.64 |
| ▸ | THPO | P40225 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28285432 | 0.98 | LMNA (0.61) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| SCHEMBL31170763 | 0.85 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| SCHEMBL2336321 | 0.85 | LMNA (0.58) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| SCHEMBL751713 | 0.82 | LMNA (0.56) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| Phenanthroline SCHEMBL29354015 | 0.78 | CCR1 (1.00) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| Phenanthroline SCHEMBL8312 | 0.78 | CCR1 (1.00) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| Phenanthroline SCHEMBL8845760 | 0.78 | CCR1 (1.00) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| Phenanthroline SCHEMBL29367277 | 0.78 | CCR1 (1.00) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| Phenanthroline SCHEMBL18113452 | 0.77 | CCR1 (0.84) | LMNAKDM4ESMN1; SMN2MMP2TSHR | |
| SCHEMBL1282008 | 0.77 | CCR1 (0.75) | LMNAKDM4ESMN1; SMN2MMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 935 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119702019-A | Catalyst for catalyzing selective hydrogenation of quinoline and preparation method thereof | 湘潭大学 | 2025-03-28 | — | — | CN | claimed |
| CN-110270295-B | Preparation method of amino-substituted benzopyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-110270295-A | Preparation method of amino-substituted phenylpropylpyridine nitrogen-containing heterocycle | 北京六合宁远科技有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-110041905-A | Fluorescence and the dual luminescent material of phosphorescence with switching effect and preparation method thereof | 华中科技大学 | 2019-07-23 | — | — | CN | claimed |
| CN-104876863-B | Fluorescent probe compound and preparation method and application thereof | 北京农学院 | 2017-02-22 | — | — | CN | claimed |
| CN-105753838-A | Novel high-regioselectivity amination method of quinoline derivatives | 安阳师范学院 | 2016-07-13 | — | — | CN | claimed |
| CN-104876863-A | Fluorescent probe compound and preparation method and application thereof | UNIV BEIJING AGRICULT | 2015-09-02 | — | — | CN | claimed |
| CN-104592109-A | Method for preparing 8-bromoquinoline derivative | Hunan huateng pharmaceutical co ltd | 2015-05-06 | — | — | CN | claimed |
| CN-103467374-A | Synthesis method of 8-bromine-4-carboxyl quinoline | CHEMFUTURE PHARMATECH JIANGSU CO LTD | 2013-12-25 | — | — | CN | claimed |
| CN-101602723-A | The preparation method of 2-methyl-8-quinolylamine | UNIV HUNAN (CN) | 2009-12-16 | — | — | CN | claimed |
| CN-100422201-C | Arylation method for the functionalization of O-allyl erythromycin derivatives | ABBOTT LAB (US) | 2008-10-01 | — | — | CN | claimed |
| EP-1399458-B1 | AN ARYLATION METHOD FOR THE FUNCTIONALIZATION OF O-ALLYL ERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2005-08-03 | — | — | EP | claimed |
| CN-1633443-A | Arylation method for the functionalization of O-allyl erythromycin derivatives | ABBOTT LAB (US) | 2005-06-29 | — | — | CN | claimed |
| EP-1399458-A1 | AN ARYLATION METHOD FOR THE FUNCTIONALIZATION OF O-ALLYL ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 2004-03-24 | — | — | EP | claimed |
| US-20030125531-A1 | Arylation method for the functionalization of O-allyl erythromycin derivatives | ABBVIE INC. | 2003-07-03 | — | — | US | claimed |
| WO-2002096922-A1 | AN ARYLATION METHOD FOR THE FUNCTIONALIZATION OF O-ALLYL ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 2002-12-05 | — | — | WO | claimed |
| EP-0365863-B1 | Novel quinolyloxazole-2-ones useful as proteinkinase C inhibitors | MERRELL DOW PHARMA (US) | 1994-08-17 | — | — | EP | claimed |
| US-4999431-A | Reacting A Bromoquinoline Compound With Butyllithium And An N-Methyl-N-Methoxyalkanamide; Intermediates for Quinolyloxazole-2-ones | MERRELL DOW PHARMACEUTICALS (US) | 1991-03-12 | — | — | US | claimed |
| CN-1042145-A | New quinolyl azoles-2-ketone compounds as inhibitors of protein kinase C | MERRELL DOW PHARMA (US) | 1990-05-16 | — | — | CN | claimed |
| EP-0365863-A2 | Novel quinolyloxazole-2-ones useful as proteinkinase C inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-05-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125531-A1 | Arylation method for the functionalization of O-allyl erythromycin derivatives | EEF2K, DEK, FRK | LMNA 4574/4885KDM4E 735/4885SMN1; SMN2 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.