SCHEMBL1282008

SCHEMBL1282008

c1cnc2c(-c3cccc4cccnc34)cccc2c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.75
CCR8 P51685 5/20 0.75
LMNA P02545 4/20 0.75
CCR5 P51681 3/20 0.75
KDM4E B2RXH2 3/20 0.75
MMP2 P08253 2/20 0.75
TSHR P16473 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
GMNN O75496 1/20 0.75
TP53 P04637 1/20 0.75
HSP90AA1 P07900 1/20 0.75
CYP3A4 P08684 1/20 0.75
CYP2D6 P10635 1/20 0.75
MAPT P10636 1/20 0.75
MMP9 P14780 1/20 0.75
ALOX15 P16050 1/20 0.75
NFKB1 P19838 1/20 0.75
MMP8 P22894 1/20 0.75
THPO P40225 1/20 0.75
MTOR P42345 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30184687 1.00 CCR1 (0.75) CCR1CCR8LMNACCR5KDM4E
SCHEMBL12853981 0.95 LMNA (0.68) CCR1CCR8LMNACCR5KDM4E
SCHEMBL29011948 0.87 MMP2 (0.59) CCR1CCR8LMNACCR5KDM4E
SCHEMBL2999658 0.87 KDM4E (0.58) CCR1CCR8LMNACCR5KDM4E
SCHEMBL28008054 0.87 KDM4E (0.58) CCR1CCR8LMNACCR5KDM4E
SCHEMBL12854080 0.87 MMP2 (0.58) CCR1CCR8LMNACCR5KDM4E
SCHEMBL17334526 0.86 CCR1 (0.62) CCR1CCR8LMNACCR5KDM4E
SCHEMBL2922581 0.86 CCR1 (0.62) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL29354015 0.86 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL8845760 0.86 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115572258-A C 2 Preparation method of axial chiral biquinoline framework compound 中国科学院成都有机化学有限公司 2023-01-06 CN claimed
CN-115572258-A C 2 Preparation method of axial chiral biquinoline framework compound 中国科学院成都有机化学有限公司 2023-01-06 CN disclosed
CN-115572258-A C 2 Preparation method of axial chiral biquinoline framework compound 中国科学院成都有机化学有限公司 2023-01-06 CN disclosed
EP-2855344-B1 GRAPHENE NANORIBBONS WITH CONTROLLED MODIFICATIONS MAX PLANCK GESELLSCHAFT (DE) 2022-10-26 EP disclosed
CN-208690304-U Stop the OLED device of composite construction with hole transport 棓诺(苏州)新材料有限公司 2019-04-02 CN disclosed
US-9676755-B2 Graphene nanoribbons with controlled modifications BASF SE (DE) 2017-06-13 US disclosed
US-9527743-B2 Process for preparing graphene nanoribbons BASF SE (DE) 2016-12-27 US disclosed
US-20150225244-A1 PROCESS FOR PREPARING GRAPHENE NANORIBBONS BASF SE (DE) 2015-08-13 US disclosed
EP-2897901-A1 PROCESS FOR PREPARING GRAPHENE NANORIBBONS BASF SE (DE) 2015-07-29 EP disclosed
US-20150158850-A1 GRAPHENE NANORIBBONS WITH CONTROLLED MODIFICATIONS BASF SE (DE) 2015-06-11 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150158850-A1 GRAPHENE NANORIBBONS WITH CONTROLLED MODIFICATIONS SPIN3, SHROOM3, WNT3 CCR1 3750/4885CCR8 2940/4885LMNA 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.