SCHEMBL196515

SCHEMBL196515

Brc1ccc(-c2cccs2)s1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.52
HDAC1 Q13547 1/20 0.52
DPP4 P27487 4/20 0.50
ALDH1A1 P00352 8/20 0.48
KDM4E B2RXH2 7/20 0.48
L3MBTL1 Q9Y468 5/20 0.48
MAPT P10636 4/20 0.48
GAA P10253 3/20 0.48
LMNA P02545 2/20 0.48
GLA P06280 2/20 0.48
NPC1 O15118 4/20 0.47
HPGD P15428 4/20 0.47
RAB9A P51151 4/20 0.47
HSD17B10 Q99714 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
POLB P06746 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
CASP1 P29466 2/20 0.47
CASP7 P55210 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL498603 0.98 DPP4 (0.53) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL4340697 0.84 SNCA (0.46) LTA4HHDAC1DPP4ALDH1A1KDM4E
Alpha-Terthienyl SCHEMBL147274 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL2742433 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL14703073 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL23611278 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL1105086 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL499333 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL13707354 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E
SCHEMBL13707359 0.83 DPP4 (0.65) LTA4HHDAC1DPP4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368351-B Preparation method and application of polysubstituted oxazole compound 广东工业大学 2025-03-25 CN claimed
WO-2021019559-A1 SYNTHESIS OF 5-(3-PYRIDYL)-2,2'-BITHIOPHENE(SENSITIZER) FERMENTA BIOTECH LIMITED (IN) 2021-02-04 WO claimed
CN-111592739-A Preparation method of electromagnetic shielding plastic 湖南七纬科技有限公司 2020-08-28 CN claimed
CN-108912614-B Electromagnetic shielding plastic and preparation method thereof 广东佳瑞达科技有限公司 2020-08-18 CN claimed
EP-2617754-A1 FLUORENE CONTAINING ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF Ocean's King Lighting Science&Technology Co., Ltd. (CN) 2013-07-24 EP claimed
US-20260035592-A1 CATIONICALLY POLYMERIZABLE RESIN COMPOSITION FOR THREE-DIMENSIONAL PHOTOFABRICATION AND METHOD FOR PRODUCING THREE-DIMENSIONAL PHOTOFABRICATED PRODUCT TOKUYAMA DENTAL CORPORATION (JP) 2026-02-05 US disclosed
CN-115368351-B Preparation method and application of polysubstituted oxazole compound 广东工业大学 2025-03-25 CN disclosed
US-12202954-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-01-21 US disclosed
US-20240199882-A1 THIENYL-DIBENZOAZEPINES AND THEIR DERIVATIVES AS DONORS FOR XANTHENE-BASED SHORT-WAVE INFRARED (SWIR) DYES MISSISSIPPI STATE UNIVERSITY (US) 2024-06-20 US disclosed
WO-2024038705-A1 CATIONICALLY POLYMERIZABLE RESIN COMPOSITION FOR 3D STEREOLITHOGRAPHY AND METHOD FOR PRODUCING 3D STEREOLITHOGRAPHY PRODUCT 株式会社トクヤマデンタル 2024-02-22 WO disclosed
CN-116987097-A Organic conjugated molecule based on D-A-D type near infrared two-region emission and preparation method and application thereof 北京化工大学 2023-11-03 CN disclosed
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-03 US disclosed
EP-0819125-A1 THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1998-01-21 EP disclosed
US-5594021-A VASOCONSTRICTORS TEXAS BIOTECHNOLOGY CORPORATION (US) 1997-01-14 US disclosed
US-5591761-A Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION (US) 1997-01-07 US disclosed
US-5571821-A CARDIOVASCULAR DISORDERS TO MODULATE ENDOTHELIN, HYPOTENSIVE AGENTS AND VASOCONSTRICTION TEXAS BIOTECHNOLOGY CORPORATION (US) 1996-11-05 US disclosed
WO-1996031492-A1 THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1996-10-10 WO disclosed
US-5546889-A Method of manufacturing organic oriented film and method of manufacturing electronic device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-08-20 US disclosed
EP-0699191-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1996-03-06 EP disclosed
WO-1994027979-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN IMMUNOPHARMACEUTICS, INC. (US) 1994-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst PPOX, TST, COX6C LTA4H 2216/4885HDAC1 3582/4885DPP4 1694/4885
US-20260035592-A1 CATIONICALLY POLYMERIZABLE RESIN COMPOSITION FOR THREE-DIMENSIONAL PHOTOFABRICATION AND METHOD FOR PRODUCING THREE-DIMENSIONAL PHOTOFABRICATED PRODUCT TERB1, CAD, C9 LTA4H 199/4885HDAC1 1506/4885DPP4 3718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.