SCHEMBL19652020

SCHEMBL19652020

CC1=C(C#N)C(=O)N(C)C(=O)/C1=C\c1ccc(N(c2ccccc2)c2ccccc2)o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.49
MAPT P10636 14/20 0.46
KMT2A Q03164 13/20 0.46
MEN1 O00255 12/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NEK6 Q9HC98 1/20 0.44
ALDH1A1 P00352 11/20 0.43
POLB P06746 9/20 0.43
NPC1 O15118 1/20 0.42
IDE P14735 1/20 0.42
KDM4E B2RXH2 8/20 0.41
MCL1 Q07820 6/20 0.41
L3MBTL1 Q9Y468 6/20 0.41
RECQL P46063 5/20 0.41
BLM P54132 3/20 0.41
USP2 O75604 3/20 0.41
PKM P14618 3/20 0.41
GAA P10253 2/20 0.41
HPGD P15428 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19652024 0.89 ESR2 (0.43) ESR2MAPTKMT2AMEN1RAB9A
SCHEMBL19652003 0.83 MAPT (0.47) ESR2MAPTKMT2AMEN1RAB9A
SCHEMBL19652021 0.79 MAPT (0.72) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL17790364 0.77 MAPT (0.38) ESR2MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL14015217 0.75 MAPT (0.42) ESR2MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL19652009 0.74 MAPT (0.58) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL12436620 0.73 ESR2 (0.59) ESR2MAPTKMT2AMEN1NEK6
SCHEMBL12435517 0.72 ESR2 (0.55) ESR2MAPTKMT2AMEN1RAB9A
SCHEMBL14583824 0.72 ESR2 (0.55) ESR2MAPTKMT2AMEN1NEK6
SCHEMBL19652005 0.71 KMT2A (0.48) MAPTKMT2AMEN1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 ESR2 955/4885MAPT 2370/4885KMT2A 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.