SCHEMBL19652003

SCHEMBL19652003

CC1=C(C#N)/C(=C/c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)o2)C(=O)N(C)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.47
KMT2A Q03164 12/20 0.47
MEN1 O00255 11/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
RAB9A P51151 2/20 0.47
ALDH1A1 P00352 12/20 0.46
NPSR1 Q6W5P4 3/20 0.46
GFER P55789 1/20 0.46
NPC1 O15118 1/20 0.43
IDE P14735 1/20 0.43
ESR2 Q92731 1/20 0.41
POLB P06746 8/20 0.37
KDM4E B2RXH2 7/20 0.36
HPGD P15428 6/20 0.36
L3MBTL1 Q9Y468 5/20 0.36
MCL1 Q07820 4/20 0.36
GAA P10253 3/20 0.36
RECQL P46063 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
MAPK1 P28482 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19652009 0.85 MAPT (0.58) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL19652020 0.83 ESR2 (0.49) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL19652025 0.81 MAPT (0.70) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL19652004 0.76 MAPT (0.63) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL19652024 0.74 ESR2 (0.43) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL19652021 0.70 MAPT (0.72) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL19658243 0.66 MAPT (0.48) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL22108583 0.64 BRAF (0.51) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL22108463 0.64 MAPT (0.42) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL12436620 0.63 ESR2 (0.59) MAPTKMT2AMEN1ALDH1A1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 MAPT 2370/4885KMT2A 1370/4885MEN1 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.