Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454788 | 0.82 | ALOX12 (1.00) | ALOX12MAPK1HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL30122631 | 0.82 | MAPK1 (0.75) | ALOX12MAPK1HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL1682746 | 0.82 | MAPK1 (0.75) | ALOX12MAPK1HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL9611693 | 0.80 | MAPK1 (0.67) | ALOX12MAPK1HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL30293362 | 0.78 | ALOX12 (0.46) | ALOX12HRH3MAPK1ALDH1A1MEN1 | |
| SCHEMBL1963855 | 0.77 | HSD17B10 (0.52) | ALOX12MAPK1HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL22021644 | 0.76 | ALOX12 (0.44) | ALOX12HRH3MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL540767 | 0.76 | MAPK1 (0.67) | ALOX12MAPK1HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL2631381 | 0.75 | MAPK1 (0.74) | ALOX12MAPK1HSD17B10POLBSMN1; SMN2 | |
| SCHEMBL15302024 | 0.75 | NPC1 (0.70) | HRH3HSD17B10POLBSMN1; SMN2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-9486455-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486455-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486455-B2 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-8552009-B2 | Substituted pyrimido 4.5-d pyrimidin-4-one compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. | 2013-10-08 | — | — | US | disclosed |
| US-20100152209-A1 | Compounds for Modulating TRPV3 Function | HYDRA BIOSCIENCES INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100152209-A1 | Compounds for Modulating TRPV3 Function | HYDRA BIOSCIENCES INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES INC. (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2008140750-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| WO-2007056124-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155417-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | ALOX12 736/4885HRH3 1036/4885MAPK1 2094/4885 |
| US-20090018147-A1 | Compounds for modulating TRPV3 function | TRPV3, TRPV1, TRPV4 | ALOX12 736/4885HRH3 1036/4885MAPK1 2094/4885 |
| US-20100152209-A1 | Compounds for Modulating TRPV3 Function | TRPV3, TRPV1, TRPV4 | ALOX12 736/4885HRH3 1036/4885MAPK1 2094/4885 |
| US-20070179164-A1 | Compounds for modulating TRPV3 function | TRPV3, TRPV1, TRPV4 | ALOX12 736/4885HRH3 1036/4885MAPK1 2094/4885 |
| US-20170224687-A1 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | TRPV3, TRPV1, TRPV4 | ALOX12 736/4885HRH3 1036/4885MAPK1 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.