SCHEMBL19653786

SCHEMBL19653786

c1ccc(-c2nc3c4ccccc4c4ccccc4c3nc2-n2c3ccccc3c3c4c5ccccc5n(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)c4ccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
RXFP1 Q9HBX9 1/20 0.33
RAC2 P15153 1/20 0.33
RAC3 P60763 1/20 0.33
CDC42 P60953 1/20 0.33
RAC1 P63000 1/20 0.33
NPY5R Q15761 1/20 0.32
KMT2A Q03164 3/20 0.32
IL1R1 P14778 1/20 0.32
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
PTGER4 P35408 1/20 0.31
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
ADORA2B P29275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653799 0.93 L3MBTL1 (0.44) L3MBTL1KDM4EATMRXFP1KMT2A
SCHEMBL19653804 0.91 KDM4E (0.38) L3MBTL1KDM4EATMRXFP1KMT2A
SCHEMBL19653796 0.90 ATM (0.36) L3MBTL1KDM4EATMRXFP1KMT2A
SCHEMBL19653782 0.89 HPGD (0.33) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL19655334 0.88 L3MBTL1 (0.47) L3MBTL1KDM4EATMRXFP1NPY5R
SCHEMBL19655105 0.88 PTGER1 (0.35) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL23183879 0.87 KDM4E (0.42) L3MBTL1KDM4EATMRXFP1RAC2
SCHEMBL19653911 0.87 KDM4E (0.42) L3MBTL1KDM4EATMRXFP1RAC2
SCHEMBL19653808 0.86 KDM4E (0.31) KDM4EKMT2AALDH1A1MAPTMEN1
SCHEMBL19653802 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711977-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-11711977-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-24 US disclosed
US-10985328-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-20 US disclosed
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10985328-B2 Organic electroluminescent materials and devices AZI2, INMT, PIR L3MBTL1 2843/4885KDM4E 1575/4885ATM 1995/4885
US-11711977-B2 Organic electroluminescent materials and devices AZI2, INMT, PIR L3MBTL1 2843/4885KDM4E 1575/4885ATM 1995/4885
US-20170346021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR L3MBTL1 2843/4885KDM4E 1575/4885ATM 1995/4885
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885
US-20210193934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AZI2, INMT, PIR L3MBTL1 2843/4885KDM4E 1575/4885ATM 1995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.