Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763363 | 0.80 | CYP1A2 (0.65) | KDM4ETSHRPOLBTDP1CYP1A2 | |
| SCHEMBL2619346 | 0.79 | HRH3 (0.59) | KDM4ETSHRPOLBTDP1CYP1A2 | |
| SCHEMBL18513634 | 0.79 | HRH3 (0.51) | KDM4EPOLBCYP1A2CYP2D6HRH3 | |
| SCHEMBL230753 | 0.78 | HRH1 (0.73) | TDP1CYP1A2CYP2D6HRH3HRH1 | |
| SCHEMBL29485678 | 0.78 | HRH1 (0.73) | TDP1CYP1A2CYP2D6HRH3HRH1 | |
| SCHEMBL11324240 | 0.77 | HRH3 (0.47) | KDM4ETSHRPOLBTDP1CYP1A2 | |
| SCHEMBL30398570 | 0.76 | HRH3 (0.55) | KDM4EPOLBCYP1A2CYP2D6HRH3 | |
| SCHEMBL487617 | 0.76 | HRH3 (0.55) | KDM4EPOLBCYP1A2CYP2D6HRH3 | |
| Bromide SCHEMBL28641396 | 0.76 | HRH1 (0.70) | TDP1CYP1A2CYP2D6HRH3HRH1 | |
| SCHEMBL3840575 | 0.76 | HRH3 (0.56) | KDM4ETSHRPOLBTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340597-A1 | LONG ACTING PHARMACEUTICAL COMPOSITION OF PROTEASE INHIBITOR | TAIMED BIOLOGICS, INC. (TW) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340597-A1 | LONG ACTING PHARMACEUTICAL COMPOSITION OF PROTEASE INHIBITOR | PRSS1, DNPEP, SERPINB1 | KDM4E 841/4885TSHR 4771/4885POLB 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.