Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966409 | 0.89 | LCK (0.42) | LCKRXRARORCHSD17B10CSNK2A2 | |
| SCHEMBL1964379 | 0.86 | KIF11 (0.40) | KIF11CYP2C9LCKRORCHSD17B10 | |
| SCHEMBL1964840 | 0.81 | LCK (0.47) | LCKRXRARORCHSD17B10CSNK2A2 | |
| SCHEMBL1965510 | 0.81 | HSD17B10 (0.42) | LCKRORCHSD17B10CSNK2A2CSNK2B | |
| SCHEMBL1964624 | 0.81 | LCK (0.45) | CYP2C9LCKRORCHSD17B10CSNK2A2 | |
| SCHEMBL1973510 | 0.80 | HSD17B10 (0.44) | LCKRXRARORCHSD17B10CSNK2A2 | |
| SCHEMBL1967011 | 0.79 | LCK (0.45) | LCKRXRARORCHSD17B10CSNK2A2 | |
| SCHEMBL1970564 | 0.79 | LCK (0.41) | LCKRORCHSD17B10CSNK2A2CSNK2B | |
| SCHEMBL1967636 | 0.78 | LCK (0.46) | LCKRORCHSD17B10CSNK2A2CSNK2B | |
| SCHEMBL1972728 | 0.78 | LCK (0.38) | KIF11CYP2C9LCKRXRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | claimed |