SCHEMBL19655210

SCHEMBL19655210

c1ccc(-c2nc3ccccc3nc2-c2cccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccc7ccccc7c6)c5c43)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
GAA P10253 3/20 0.39
HPGD P15428 1/20 0.38
HSD17B10 Q99714 2/20 0.36
POLB P06746 1/20 0.36
PDE10A Q9Y233 3/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ATM Q13315 1/20 0.36
LMNA P02545 4/20 0.35
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
THRB P10828 1/20 0.35
MAPK9 P45984 1/20 0.35
MAPK10 P53779 1/20 0.35
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655219 0.92 L3MBTL1 (0.40) MEN1KMT2AGAAHPGDHSD17B10
SCHEMBL19655196 0.92 L3MBTL1 (0.44) MEN1KMT2AGAAHPGDHSD17B10
SCHEMBL19655195 0.91 L3MBTL1 (0.41) MEN1KMT2AGAAHSD17B10POLB
SCHEMBL19655194 0.90 KMT2A (0.41) MEN1KMT2AGAAHPGDHSD17B10
SCHEMBL19655206 0.89 L3MBTL1 (0.43) MEN1KMT2AGAAHSD17B10POLB
SCHEMBL19655321 0.89 L3MBTL1 (0.40) MEN1KMT2AGAAHPGDHSD17B10
SCHEMBL19655218 0.89 L3MBTL1 (0.41) MEN1KMT2AGAAHPGDHSD17B10
SCHEMBL19655191 0.89 L3MBTL1 (0.41) MEN1KMT2AGAAHSD17B10POLB
SCHEMBL19655185 0.88 HPGD (0.38) MEN1KMT2AGAAHPGDHSD17B10
SCHEMBL19655211 0.88 GSR (0.40) MEN1KMT2AGAAHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO MEN1 2827/4885KMT2A 3170/4885GAA 2621/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO MEN1 2827/4885KMT2A 3170/4885GAA 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.