SCHEMBL19655196

SCHEMBL19655196

c1ccc(-c2nc3ccccc3nc2-c2cccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccccc6)c5c43)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.44
KDM4E B2RXH2 4/20 0.44
ATM Q13315 2/20 0.44
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
GAA P10253 4/20 0.42
HSD17B10 Q99714 2/20 0.40
POLB P06746 1/20 0.40
ALDH1A1 P00352 6/20 0.39
LMNA P02545 3/20 0.39
THRB P10828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
IL1R1 P14778 1/20 0.38
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
MAPK1 P28482 1/20 0.37
TLR9 Q9NR96 1/20 0.37
HPGD P15428 1/20 0.37
CFTR P13569 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655191 0.97 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655218 0.97 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655195 0.96 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655194 0.96 KMT2A (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655206 0.95 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655201 0.94 KMT2A (0.40) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655399 0.93 MEN1 (0.40) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655210 0.92 MEN1 (0.39) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19655211 0.92 GSR (0.40) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL22141634 0.91 KDM4E (0.41) L3MBTL1KDM4EATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.