SCHEMBL19655253

SCHEMBL19655253

c1ccc(-c2nc3c4ccccc4c4ccccc4c3nc2-c2cccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc7c6sc6ccccc67)c5c43)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
MAPT P10636 2/20 0.31
RXFP1 Q9HBX9 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655192 0.91 MEN1 (0.34) TNKSTNKS2MAPTRXFP1KDM4E
SCHEMBL19655250 0.89 LIMK1 (0.34)
SCHEMBL19655233 0.87 TNKS (0.31) TNKSTNKS2
SCHEMBL26413297 0.86 TNKS (0.37) TNKSTNKS2MAPTRXFP1KDM4E
SCHEMBL17809251 0.86 TNKS (0.34) TNKSTNKS2MAPTRXFP1KDM4E
SCHEMBL19662205 0.86 MAPT (0.30) MAPTRXFP1
SCHEMBL26413294 0.85 TNKS (0.36) TNKSTNKS2MAPTRXFP1KDM4E
SCHEMBL19655248 0.85 L3MBTL1 (0.42) MAPTRXFP1KDM4EATML3MBTL1
SCHEMBL17809255 0.85 TNKS (0.33) TNKSTNKS2MAPTRXFP1KDM4E
SCHEMBL17809257 0.84 MAPT (0.34) TNKSTNKS2MAPTRXFP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO TNKS 2604/4885TNKS2 2886/4885MAPT 2438/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO TNKS 2604/4885TNKS2 2886/4885MAPT 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.