SCHEMBL19655322

SCHEMBL19655322

c1ccc(-c2nc3ccccc3nc2-c2cccc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3n5-c3cccc4ccccc34)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.40
KDM4E B2RXH2 5/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
ATM Q13315 2/20 0.39
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
POLB P06746 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GAA P10253 3/20 0.36
ALDH1A1 P00352 5/20 0.35
LMNA P02545 3/20 0.35
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTT P42858 1/20 0.34
PDE10A Q9Y233 3/20 0.33
TLR9 Q9NR96 1/20 0.33
HPGD P15428 1/20 0.33
RAD51 Q06609 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655308 0.90 L3MBTL1 (0.49) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL19653933 0.90 GSR (0.39) GSRKDM4EL3MBTL1ATMKMT2A
SCHEMBL19655311 0.89 L3MBTL1 (0.44) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL19655211 0.88 GSR (0.40) GSRKDM4EL3MBTL1ATMKMT2A
SCHEMBL19655307 0.88 L3MBTL1 (0.46) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL19655405 0.88 L3MBTL1 (0.46) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL19655329 0.88 L3MBTL1 (0.46) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL19655321 0.87 L3MBTL1 (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL19655319 0.87 L3MBTL1 (0.45) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL19655314 0.87 L3MBTL1 (0.45) KDM4EL3MBTL1ATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO GSR 545/4885KDM4E 2543/4885L3MBTL1 2020/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO GSR 545/4885KDM4E 2543/4885L3MBTL1 2020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.