SCHEMBL19655335

SCHEMBL19655335

c1ccc(-n2c3ccccc3c3cc4c(cc32)c2ccccc2n4-c2cnc3c4ccccc4c4ccccc4c3n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ATM Q13315 1/20 0.49
MAPK1 P28482 3/20 0.33
HTT P42858 1/20 0.32
KMT2A Q03164 3/20 0.32
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.31
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAT2A P31153 1/20 0.31
MAPK8 P45983 2/20 0.31
IL1R1 P14778 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
MKNK1 Q9BUB5 1/20 0.30
MKNK2 Q9HBH9 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655355 0.95 KDM4E (0.44) KDM4EL3MBTL1ATMMAT2A
SCHEMBL19655145 0.93 KDM4E (0.35) KDM4EL3MBTL1ATMMKNK1MKNK2
SCHEMBL17464158 0.91 L3MBTL1 (0.45) KDM4EL3MBTL1ATMMAPK1HTT
SCHEMBL16231074 0.91 L3MBTL1 (0.45) KDM4EL3MBTL1ATMMAPK1HTT
SCHEMBL19655339 0.90 KDM4E (0.39) KDM4EL3MBTL1ATMHTTKMT2A
SCHEMBL17464161 0.90 KDM4E (0.42) KDM4EL3MBTL1ATMMAPK1KMT2A
SCHEMBL23072397 0.89 KDM4E (0.38) KDM4EL3MBTL1ATMHTTKMT2A
SCHEMBL19655337 0.89 KDM4E (0.36) KDM4EL3MBTL1ATM
SCHEMBL19653820 0.88 KDM4E (0.42) KDM4EL3MBTL1ATMMAPK1KMT2A
SCHEMBL19655357 0.87 ALDH1A1 (0.36) KDM4EL3MBTL1ATMALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO KDM4E 2543/4885L3MBTL1 2020/4885ATM 3559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO KDM4E 2543/4885L3MBTL1 2020/4885ATM 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.