SCHEMBL19655336

SCHEMBL19655336

c1ccc(-c2ccc(-c3nc4c5ccccc5c5ccccc5c4nc3-n3c4ccccc4c4cc5c(cc43)c3ccccc3n5-c3ccccc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
NPY5R Q15761 1/20 0.34
KMT2A Q03164 4/20 0.34
IL1R1 P14778 1/20 0.34
HDAC4 P56524 1/20 0.34
ALDH1A1 P00352 4/20 0.33
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
HTT P42858 1/20 0.33
RXFP1 Q9HBX9 2/20 0.33
PTGER4 P35408 1/20 0.33
DHODH Q02127 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
HSP90AA1 P07900 1/20 0.32
AVPR1A P37288 1/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655333 0.97 KDM4E (0.41) L3MBTL1KDM4EATMNPY5RKMT2A
SCHEMBL19655334 0.97 L3MBTL1 (0.47) L3MBTL1KDM4EATMNPY5RKMT2A
SCHEMBL19655341 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19655415 0.92 KDM4E (0.37) L3MBTL1KDM4EATMNPY5RKMT2A
SCHEMBL19655380 0.91 L3MBTL1 (0.49) L3MBTL1KDM4EATMNPY5RKMT2A
SCHEMBL19655346 0.89 KDM4E (0.42) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL19655361 0.87 KDM4E (0.36) L3MBTL1KDM4EATMNPY5RKMT2A
SCHEMBL19655274 0.86 KDM4E (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19653786 0.86 L3MBTL1 (0.41) L3MBTL1KDM4EATMNPY5RKMT2A
SCHEMBL12268768 0.86 L3MBTL1 (0.49) L3MBTL1KDM4EATMNPY5RKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO L3MBTL1 2020/4885KDM4E 2543/4885ATM 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.