SCHEMBL19655356

SCHEMBL19655356

c1ccc(-c2nc3c4ccccc4c4ccccc4c3nc2-n2c3ccccc3c3cc4c(cc32)c2ccccc2n4-c2cccc3ccccc23)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.36
ALDH1A1 P00352 4/20 0.33
TDP1 Q9NUW8 2/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
HPGD P15428 1/20 0.32
NPY5R Q15761 1/20 0.31
MAPK1 P28482 2/20 0.31
NPC1 O15118 1/20 0.31
KDM4E B2RXH2 2/20 0.31
LMNA P02545 2/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655415 0.90 KDM4E (0.37) ALDH1A1TDP1HPGDNPY5RMAPK1
SCHEMBL19653823 0.88 GSR (0.36) GSRALDH1A1TDP1CNR1CNR2
SCHEMBL19655301 0.87 GSR (0.44) GSRALDH1A1TDP1HPGDKDM4E
SCHEMBL19655240 0.87 GSR (0.37) GSRALDH1A1TDP1CNR1CNR2
SCHEMBL19655334 0.85 L3MBTL1 (0.47) ALDH1A1NPY5RMAPK1KDM4EHTT
SCHEMBL19655299 0.85 GSR (0.42) GSRALDH1A1TDP1HPGDNPY5R
SCHEMBL19655351 0.84 TNKS (0.33) MAPT
SCHEMBL19655348 0.84 LIMK1 (0.36)
SCHEMBL19655333 0.83 KDM4E (0.41) ALDH1A1HPGDNPY5RMAPK1KDM4E
SCHEMBL19655336 0.83 L3MBTL1 (0.45) ALDH1A1NPY5RMAPK1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO GSR 545/4885ALDH1A1 2673/4885TDP1 2427/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO GSR 545/4885ALDH1A1 2673/4885TDP1 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.