SCHEMBL19656191

SCHEMBL19656191

CC(=CCC(Br)(Br)c1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.46
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
HTT P42858 2/20 0.39
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KCNN4 O15554 1/20 0.36
APEX1 P27695 3/20 0.36
CYP1A2 P05177 1/20 0.35
ALOX15 P16050 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19656195 0.82 AKR1C3 (0.43) AKR1C3ALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL5469921 0.74 AKR1C3 (0.42) AKR1C3ALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL2772442 0.73 AKR1C3 (0.37) AKR1C3CYP2C9MAPT
SCHEMBL19990999 0.71 KIF11 (0.46) AKR1C3TSHRCYP2C9CYP2C19HIF1A
SCHEMBL2528170 0.71 AKR1C3 (0.40) AKR1C3ALDH1A1TSHRCYP2C9KMT2A
SCHEMBL2072809 0.71 AKR1C3 (0.50) AKR1C3ALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL30528 0.71 CYP2C9 (0.51) AKR1C3ALDH1A1CYP2C9HTTKMT2A
SCHEMBL6255791 0.71 AKR1C3 (0.50) AKR1C3ALDH1A1TSHRCYP2C9CYP2C19
SCHEMBL30530 0.71 CYP2C9 (0.51) AKR1C3ALDH1A1CYP2C9HTTKMT2A
SCHEMBL3190683 0.70 ESR1 (0.51) AKR1C3ALDH1A1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10655037-B2 Adhesive composition for polarizing plate, adhesive film for polarizing plate comprising the same, polarizing plate comprising the same and display device comprising the same SAMSUNG SDI CO., LTD. (KR) 2020-05-19 US disclosed
US-20180044563-A1 ADHESIVE COMPOSITION FOR POLARIZING PLATE, ADHESIVE FILM FOR POLARIZING PLATE COMPRISING THE SAME, POLARIZING PLATE COMPRISING THE SAME AND DISPLAY DEVICE COMPRISING THE SAME Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) 2018-02-15 US disclosed
US-9834708-B2 Adhesive composition for polarizing plate, adhesive film for polarizing plate comprising the same, polarizing plate comprising the same and display device comprising the same SAMSUNG SDI CO., LTD. (KR) 2017-12-05 US disclosed