SCHEMBL2072809

SCHEMBL2072809

CC(=CC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.50
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP2C9 P11712 1/20 0.40
KCNN4 O15554 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP1A2 P05177 2/20 0.39
APEX1 P27695 7/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6255791 1.00 AKR1C3 (0.50) AKR1C3MAPTKMT2ACYP2C9KCNN4
SCHEMBL11298115 0.89 AKR1C3 (0.42) AKR1C3MAPTKMT2ACYP2C9CYP2C19
SCHEMBL11298112 0.89 AKR1C3 (0.42) AKR1C3MAPTKMT2ACYP2C9CYP2C19
SCHEMBL8019098 0.84 MAPT (0.47) AKR1C3MAPTKMT2AKCNN4CYP2C19
SCHEMBL11032442 0.82 KCNN4 (0.41) AKR1C3MAPTKMT2AKCNN4CYP1A2
SCHEMBL11032439 0.82 KCNN4 (0.41) AKR1C3MAPTKMT2AKCNN4CYP1A2
SCHEMBL6351577 0.82 L3MBTL1 (0.41) AKR1C3KMT2AHDAC6CYP2D6ALDH1A1
SCHEMBL6930225 0.82 AKR1C3 (0.48) AKR1C3MAPTKMT2ACYP2C9KCNN4
SCHEMBL1469914 0.82 AKR1C3 (0.48) AKR1C3MAPTKMT2ACYP2C9KCNN4
SCHEMBL6930231 0.82 AKR1C3 (0.48) AKR1C3MAPTKMT2ACYP2C9KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10920000-B2 Light diffusing agent, light diffusing resin composition and molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-16 US claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
EP-2404940-B1 Method for producing polymer composition and polymer composition INCTEC INC (JP) 2014-12-24 EP claimed
WO-2008015696-A2 PROCESS FOR PREPARING CICLESONIDE CADILA HEALTHCARE LIMITED (IN) 2008-02-07 WO claimed
EP-0034337-B1 A PROCESS FOR THE OPTICAL RESOLUTION OF A RACEMIC MIXTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-10-24 EP claimed
EP-3191590-B1 SORBENT MATERIAL FOR SEPARATING BIO-MACROMOLECULES QUANTUMDX GROUP LTD (GB) 2024-02-21 EP disclosed
US-11834390-B2 Adhesive composition NIPPON SODA CO., LTD. (JP) 2023-12-05 US disclosed
CN-115837174-A Organogel or liquid chromatography F·帕尔芒捷 2023-03-24 CN disclosed
US-20210347726-A1 ADHESIVE COMPOSITION NIPPON SODA CO., LTD. (JP) 2021-11-11 US disclosed
EP-3862407-A1 ADHESIVE COMPOSITION Nippon Soda Co., Ltd. (JP) 2021-08-11 EP disclosed
US-11078355-B2 (Meth)acrylic copolymer, resin composition, molded body of same, and method for producing molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-08-03 US disclosed
US-10920000-B2 Light diffusing agent, light diffusing resin composition and molded body MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-02-16 US disclosed
WO-2003048176-A1 CATALYST FOR PRODUCING (CO)POLYMERS OF (METH)ACRYLIC COMPOUNDS Röhm GmbH & Co. KG (DE) 2003-06-12 WO disclosed
WO-2003006449-A1 METHOD FOR THE PREPARATION OF ESCITALOPRAM H. LUNDBECK A/S (DK) 2003-01-23 WO disclosed
EP-1231227-A1 POLY(PHOSPHONOARYLACETYLENE) AND CHIRAL SENSOR COMPRISING THE SAME Japan Science and Technology Corporation (JP) 2002-08-14 EP disclosed
WO-2001072852-A1 METHOD FOR PRODUCING POLYMERS AND COPOLYMERS OF ALPHA-SUBSTITUTED ACRYLIC COMPOUNDS AND THE RESULTING POLYMERS Röhm GmbH & Co. KG (DE) 2001-10-04 WO disclosed
EP-0586385-B1 ENANTIOMER SEPARATING PROCESS ON CHIRAL SEPARATION PHASES BY MEANS OF A CONTINUOUS COUNTER-CURRENT CHROMATOGRAPHY PROCESS BAYER AG (DE) 1996-11-06 EP disclosed
EP-0586385-A1 ENANTIOMER SEPARATING PROCESS ON CHIRAL SEPARATION PHASES BY MEANS OF A CONTINUOUS COUNTER-CURRENT CHROMATOGRAPHY PROCESS. BAYER AG (DE) 1994-03-16 EP disclosed
WO-1992016274-A1 ENANTIOMER SEPARATING PROCESS ON CHIRAL SEPARATION PHASES BY MEANS OF A CONTINUOUS COUNTER-CURRENT CHROMATOGRAPHY PROCESS BAYER AKTIENGESELLSCHAFT (DE) 1992-10-01 WO disclosed
EP-0034337-B1 A PROCESS FOR THE OPTICAL RESOLUTION OF A RACEMIC MIXTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1984-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834390-B2 Adhesive composition F12, FN1, ALOX12 AKR1C3 965/4885MAPT 1791/4885KMT2A 3097/4885
US-20210347726-A1 ADHESIVE COMPOSITION F12, FN1, ALOX12 AKR1C3 965/4885MAPT 1791/4885KMT2A 3097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.