Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12737553 | 0.93 | TOP2A (0.47) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL16534602 | 0.83 | TOP2A (0.47) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL16329562 | 0.80 | TOP2A (0.55) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL17775397 | 0.69 | TOP2A (0.42) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL10959800 | 0.68 | ALDH1A1 (0.46) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL29724074 | 0.67 | TOP2A (0.50) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL28776450 | 0.67 | TOP2A (0.50) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL22015414 | 0.67 | TOP2A (0.44) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL21894264 | 0.66 | TOP2A (0.42) | TOP2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL8775559 | 0.64 | TOP2A (0.35) | TOP2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340781-A1 | OLIGOFLUORINATED CROSS-LINKED POLYMERS AND USES THEREOF | Evonik Canada Inc. (CA) | 2017-11-30 | — | — | US | disclosed |