SCHEMBL19656677

SCHEMBL19656677

CC(C)(C)c1coc(C#N)c1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.36
PGR P06401 3/20 0.31
AR P10275 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23847738 0.83 PGR (0.30) PGRAR
SCHEMBL12704800 0.70
SCHEMBL21720669 0.67 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL2003633 0.67
SCHEMBL50655 0.67 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL6898934 0.67 POLB (0.37) GABRA1GABRB2
SCHEMBL21720721 0.67 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL21718825 0.65 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL21720552 0.65 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL3367038 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210290784-A1 POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS FOR IMAGING MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (CSF1R) IN NEUROINFLAMMATION THE JOHNS HOPKINS UNIVERSITY 2021-09-23 US disclosed
US-10763449-B2 Organic light-emitting diode (OLED) display panel, fabrication method and electronic device thereof Shanghai Tianma AM-OLED Co., Ltd. (CN) 2020-09-01 US disclosed
US-20170346032-A1 ORGANIC LIGHT-EMITTING DIODE (OLED) DISPLAY PANEL, FABRICATION METHOD AND ELECTRONIC DEVICE THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210290784-A1 POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS FOR IMAGING MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (CSF1R) IN NEUROINFLAMMATION CSF1R, CSF3R, CMKLR1 KIF11 3825/4885PGR 2868/4885AR 2746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.