Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.52 |
| ▸ | SPR | P35270 | 2/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 15/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657312 | 0.87 | CREBBP (0.51) | CREBBPSPRPDE7AKDM4C | |
| SCHEMBL22822410 | 0.85 | CREBBP (0.50) | CREBBPSPRPDE7AKDM4C | |
| SCHEMBL19657750 | 0.77 | SPR (0.41) | SPRPDE7AKDM4C | |
| SCHEMBL19657665 | 0.77 | CREBBP (0.48) | CREBBPSPRPDE7A | |
| SCHEMBL19597133 | 0.76 | KDM4C (0.50) | SPRPDE7AKDM4C | |
| SCHEMBL23535754 | 0.74 | TEAD1 (0.47) | SPRPDE7AKDM4C | |
| SCHEMBL30040878 | 0.74 | TEAD1 (0.47) | SPRPDE7AKDM4C | |
| SCHEMBL23535820 | 0.74 | KDM4E (0.43) | SPR | |
| SCHEMBL30159511 | 0.74 | KDM4E (0.43) | SPR | |
| SCHEMBL19644534 | 0.74 | CNR2 (0.46) | CREBBPSPRPDE7AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |