Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.43 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657532 | 0.85 | CREBBP (0.46) | GPR142CREBBPAHRMAPK1HPGD | |
| SCHEMBL19657539 | 0.84 | GPR142 (0.44) | GPR142CREBBPAHRMAPK1HPGD | |
| SCHEMBL19643592 | 0.84 | BAZ2B (0.48) | GPR142CREBBPAHRMAPK1HPGD | |
| SCHEMBL22822708 | 0.82 | CREBBP (0.46) | GPR142CREBBPAHRMAPK1HPGD | |
| SCHEMBL19644152 | 0.81 | MAPK1 (0.61) | GPR142CREBBPAHRMAPK1HPGD | |
| SCHEMBL7563761 | 0.70 | MAPK1 (0.45) | GPR142CREBBPAHRMAPK1HPGD | |
| SCHEMBL15522980 | 0.67 | RYR2 (0.48) | MAPK1 | |
| SCHEMBL13945551 | 0.64 | DRD2 (0.59) | — | |
| SCHEMBL379244 | 0.64 | MAPK1 (0.66) | CREBBPAHRMAPK1HPGDBAZ2B | |
| SCHEMBL19657579 | 0.64 | MAPK1 (0.54) | GPR142CREBBPAHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205536-A2 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |