Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30092674 | 0.77 | RIPK1 (0.45) | RIPK1 | |
| SCHEMBL18367366 | 0.77 | RIPK1 (0.45) | RIPK1 | |
| SCHEMBL22888435 | 0.76 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL19659483 | 0.76 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL30587469 | 0.74 | RIPK1 (0.42) | RIPK1 | |
| SCHEMBL19659436 | 0.72 | — | — | |
| SCHEMBL6402101 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL7247609 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL14158496 | 0.67 | OPRM1 (0.40) | — | |
| SCHEMBL17591321 | 0.65 | PDK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017004500-A9 | BICYCLIC LACTAMS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | WO | disclosed |