Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | RORC | P51449 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318434 | 0.81 | ALDH1A1 (0.47) | TP53ALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL1966818 | 0.79 | SMN1; SMN2 (0.64) | TP53ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1968621 | 0.78 | LMNA (0.63) | ALDH1A1MAPK1RAB9AHTTMAPT | |
| SCHEMBL16857093 | 0.78 | ALDH1A1 (0.73) | TP53ALDH1A1SMN1; SMN2CYP3A4HTT | |
| SCHEMBL3309519 | 0.77 | SMN1; SMN2 (0.61) | TP53ALDH1A1RORCSMN1; SMN2MAPK1 | |
| SCHEMBL1972034 | 0.77 | LOXL2 (0.47) | ALDH1A1SMN1; SMN2PPARGNPC1RAB9A | |
| SCHEMBL5835259 | 0.77 | KMT2A (0.65) | TP53ALDH1A1EGFRRORCSMN1; SMN2 | |
| SCHEMBL31753813 | 0.75 | SMN1; SMN2 (0.57) | ALDH1A1RORCSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2585157 | 0.74 | TP53 (0.82) | TP53ALDH1A1RORCSMN1; SMN2MAPK1 | |
| SCHEMBL1456273 | 0.74 | MAPT (0.71) | TP53ALDH1A1RORCSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |