Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969659 | 0.84 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL1251440 | 0.78 | KMT2A (0.65) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL4286261 | 0.77 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL31665238 | 0.76 | SMN1; SMN2 (0.54) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL10960186 | 0.76 | ALDH1A1 (0.56) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL25143337 | 0.75 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL5799657 | 0.75 | MAPT (0.66) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL31665465 | 0.75 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL31665255 | 0.74 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL2754020 | 0.74 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |