Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.64 |
| ▸ | NPC1 | O15118 | 14/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PLTP | P55058 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4286261 | 0.84 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL1966157 | 0.84 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL2754020 | 0.81 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL25143337 | 0.80 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL8559786 | 0.79 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL31665475 | 0.78 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL2949867 | 0.78 | SMN1; SMN2 (0.62) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL25143078 | 0.77 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL25142926 | 0.77 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL7349284 | 0.77 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |