Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20919200 | 0.80 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL2573370 | 0.78 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL28236926 | 0.77 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL1966290 | 0.74 | CYP2C19 (0.30) | MEN1KMT2A | |
| SCHEMBL3431512 | 0.74 | — | — | |
| SCHEMBL25365469 | 0.73 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL28743535 | 0.73 | CYP2C19 (0.32) | MEN1KMT2A | |
| SCHEMBL23795144 | 0.73 | — | — | |
| SCHEMBL31691566 | 0.73 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL15319783 | 0.71 | TSHR (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262802-A1 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE | Novartis AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009109576-A1 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE | NOVARTIS AG (CH) | 2009-09-11 | — | — | WO | disclosed |