Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL19664269 | 1.00 | ALOX15 (0.34) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Sulfuric Acid SCHEMBL8404902 | 0.93 | TET2 (0.34) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Sulfuric Acid SCHEMBL16196070 | 0.93 | TET2 (0.34) | ALOX15HSD17B10TET2FFAR3TET3 | |
| SCHEMBL28251693 | 0.93 | ALOX15 (0.38) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Trimethylammonium SCHEMBL20907 | 0.89 | FFAR3 (0.40) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Trimethylammonium SCHEMBL141478 | 0.86 | FFAR3 (0.38) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Trimethylammonium SCHEMBL460229 | 0.86 | FFAR3 (0.38) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Trimethylammonium SCHEMBL2478116 | 0.86 | FFAR3 (0.38) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Trimethylammonium SCHEMBL9095442 | 0.86 | FFAR3 (0.38) | ALOX15HSD17B10TET2FFAR3TET3 | |
| Trimethylammonium SCHEMBL1226064 | 0.86 | FFAR3 (0.38) | ALOX15HSD17B10TET2FFAR3TET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107107461-B | Active energy ray-curable resin composition for three-dimensional molded support | 科巨希化学股份公司 | 2022-03-29 | — | — | CN | disclosed |
| EP-3254835-B1 | PRODUCTION METHOD FOR 3D MODELED OBJECT | KJ CHEMICALS CORP (JP) | 2021-06-16 | — | — | EP | disclosed |
| US-10711149-B2 | Active energy ray-curable resin composition for three-dimensional model supporting material | KJ CHEMICALS CORPORATION (JP) | 2020-07-14 | — | — | US | disclosed |
| US-10286598-B2 | Method for manufacturing three-dimensional molded product and three-dimensional molded product using the same | KJ CHEMICALS CORPORATION (JP) | 2019-05-14 | — | — | US | disclosed |
| US-20180291219-A1 | ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITION FOR THREE-DIMENSIONAL MODEL SUPPORTING MATERIAL | KJ CHEMICALS CORPORATION (JP) | 2018-10-11 | — | — | US | disclosed |
| US-20180264716-A1 | METHOD FOR MANUFACTURING THREE-DIMENSIONAL MOLDED PRODUCT AND THREE-DIMENSIONAL MOLDED PRODUCT USING THE SAME | KJ CHEMICALS CORPORATION (JP) | 2018-09-20 | — | — | US | disclosed |
| EP-3251818-A1 | ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITION FOR THREE-DIMENSIONAL MODEL SUPPORTING MATERIAL | KJ Chemicals Corporation (JP) | 2017-12-06 | — | — | EP | disclosed |