SCHEMBL185654

SCHEMBL185654

COc1ccnc2c1ccc1c(OC)ccnc12

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
SLC40A1 Q9NP59 3/20 0.48
HTR1A P08908 2/20 0.44
ADRA1D P25100 2/20 0.44
ADRA1A P35348 2/20 0.44
ADRA1B P35368 2/20 0.44
PDGFRB P09619 1/20 0.43
PDGFRA P16234 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPC1 O15118 1/20 0.42
NSD2 O96028 1/20 0.40
CASP6 P55212 1/20 0.40
G6PD P11413 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4612883 0.92 SLC40A1 (0.47) CCR1CCR5CCR8SLC40A1HTR1A
SCHEMBL8032037 0.90 CCR1 (0.69) CCR1CCR5CCR8SLC40A1HTR1A
SCHEMBL13621091 0.88 SLC40A1 (0.42) CCR1CCR5CCR8SLC40A1HTR1A
SCHEMBL8140602 0.86 SLC40A1 (0.43) CCR1CCR5CCR8SLC40A1HTR1A
SCHEMBL30492645 0.85 CCR1 (0.62) CCR1CCR5CCR8SLC40A1PDGFRB
SCHEMBL10505657 0.85 CCR1 (0.62) CCR1CCR5CCR8SLC40A1PDGFRB
SCHEMBL15195529 0.84 G6PD (0.44) SLC40A1HTR1AADRA1DADRA1AADRA1B
SCHEMBL14871760 0.84 HTR1A (0.53) SLC40A1HTR1AADRA1DADRA1AADRA1B
SCHEMBL9605472 0.84 CCR1 (0.45) CCR1CCR5CCR8SLC40A1HTR1A
SCHEMBL12564863 0.84 KDM4E (0.51) CCR1CCR5CCR8SLC40A1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1985 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146142-A1 WAVELENGTH DOWNCONVERTERS LAMBDA ENERGY LTD (GB) 2026-05-28 US claimed
US-12628491-B2 Organic-inorganic adhesion layer and its use in perovskite solar cells and modules Tandem PV (US) 2026-05-12 US claimed
EP-4683978-A1 WAVELENGTH DOWNCONVERTERS Lambda Energy Ltd (GB) 2026-01-28 EP claimed
US-12351548-B2 Method for preparing carbonyl sulfone SOOCHOW UNIVERSITY (CN) 2025-07-08 US claimed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
CN-119707617-A Method for reducing alkyne into alkene by using water as hydrogen source 长春工业大学 2025-03-28 CN claimed
WO-2025059098-A2 PHOTOCATALYTIC CARBOXYLATION OF SUBSTRATES WITH CARBON OXIDE NEW IRIDIUM INC. (US) 2025-03-20 WO claimed
WO-2025043152-A1 METHODS OF DEALKENYLATIVE AMINATION AND AZIDATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-27 WO claimed
CN-119191978-A Method for synthesizing meta-secondary alkyl substituted aryl carboxylic acid 华南理工大学 2024-12-27 CN claimed
CN-119019252-A Activation method of C-O bond of diethylene glycol dimethyl ether compound 南昌大学 2024-11-26 CN claimed
US-20120100439-A1 ELECTROLYTE SOLUTION FOR SECONDARY LITHIUM BATTERY AND SECONDARY LITHIUM BATTERY INCLUDING THE ELECTROLYTE SOLUTION SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-04-26 US claimed
US-20110224335-A1 INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME KIM SUNG-HEE 2011-09-15 US claimed
US-7935552-B2 Ink composition and method of fabricating liquid crystal display device using the same LG DISPLAY CO., LTD. (KR) 2011-05-03 US claimed
US-20100120181-A1 INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2010-05-13 US claimed
US-20090163470-A1 THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF ABBOTT LABORATORIES (US) 2009-06-25 US claimed
US-20030201194-A1 Quantitative analysis; redox systems; monitoring glucose concentration THERASENSE, INC. 2003-10-30 US claimed
EP-0958495-B1 SMALL VOLUME IN VITRO ANALYTE SENSOR THERASENSE INC (US) 2002-11-13 EP claimed
US-6120676-A DETECTION AND QUANTIFICATION OF AN ANALYTE IN SUBMICROLITER SAMPLES. THERASENSE, INC. (US) 2000-09-19 US claimed
EP-0958495-A1 SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR E. HELLER & COMPANY (US) 1999-11-24 EP claimed
WO-1998035225-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR E. HELLER & COMPANY (US) 1998-08-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163470-A1 THIAZOLYLIDINE UREA AND AMIDE DERIVATIVES AND METHODS OF USE THEREOF NMUR1, NMUR2, PAM CCR1 1787/4885CCR5 1618/4885CCR8 1368/4885
US-12351548-B2 Method for preparing carbonyl sulfone TST, CBS, STS CCR1 3677/4885CCR5 4160/4885CCR8 4540/4885
US-20260146142-A1 WAVELENGTH DOWNCONVERTERS AAAS, ALAD, MT-ND6 CCR1 4842/4885CCR5 4673/4885CCR8 4871/4885
US-12628491-B2 Organic-inorganic adhesion layer and its use in perovskite solar cells and modules EPCAM, CDH1, L1CAM CCR1 2140/4885CCR5 3549/4885CCR8 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.