Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974313 | 0.81 | FFAR1 (0.46) | CYP1A2ALOX15 | |
| SCHEMBL18374086 | 0.81 | REN (0.40) | ADRB2HTR2BALDH1A1MAPT | |
| SCHEMBL13475539 | 0.81 | TSHR (0.50) | TSHRADRB2CYP2C9HTTLMNA | |
| SCHEMBL28080918 | 0.80 | ACHE (0.59) | CYP2C9HTTLMNASMN1; SMN2TDP1 | |
| SCHEMBL18122084 | 0.80 | MAPT (0.54) | CYP2C9LMNASMN1; SMN2TDP1CYP1A2 | |
| SCHEMBL24723462 | 0.80 | HPGD (0.35) | TSHRADRB2CYP1A2ALDH1A1HPGD | |
| SCHEMBL171742 | 0.80 | NPSR1 (0.56) | CYP2C9HTTSMN1; SMN2TDP1CYP1A2 | |
| SCHEMBL31510958 | 0.80 | L3MBTL1 (0.42) | TSHRCYP2C9LMNASMN1; SMN2TDP1 | |
| SCHEMBL18122085 | 0.80 | AR (0.43) | HTR2BALDH1A1 | |
| SCHEMBL11236286 | 0.79 | CYP2C9 (0.50) | TSHRADRB2CYP2C9HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914597-B1 | PYRAZOLOPYRIDINE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2017-12-06 | — | — | EP | disclosed |