Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | PER2 | O15055 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576146 | 0.84 | PTGS1 (0.38) | PTGS1PTGS2CA2MAPTTSHR | |
| SCHEMBL1964848 | 0.79 | L3MBTL1 (0.47) | PTGS1PTGS2PER2CA2ACHE | |
| SCHEMBL1964598 | 0.78 | PTGS1 (0.39) | PTGS1PTGS2CA2TRPC5 | |
| SCHEMBL515027 | 0.77 | CA2 (0.39) | PTGS1PTGS2CA2MAPTKDM4E | |
| SCHEMBL513334 | 0.77 | CA2 (0.39) | PTGS1PTGS2PER2CA2CRY2 | |
| SCHEMBL513997 | 0.77 | PTGS1 (0.39) | PTGS1PTGS2CA2 | |
| SCHEMBL16388905 | 0.77 | PTGS1 (0.36) | PTGS1PTGS2PER2CRY2 | |
| SCHEMBL1964543 | 0.76 | PTGS1 (0.40) | PTGS1PTGS2PER2CA2CRY2 | |
| SCHEMBL16862444 | 0.76 | CA2 (0.38) | PTGS1PTGS2CA2MAPTKDM4E | |
| SCHEMBL2581430 | 0.75 | FADS1 (0.39) | PTGS1PTGS2CA2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336104-A1 | ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE | Nissan Chemical Industries, Ltd. (JP) | 2011-06-22 | — | — | EP | disclosed |