SCHEMBL19667019

SCHEMBL19667019

CC(C)(C)c1ncc(-n2ccnc2)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.46
CYP2A6 P11509 1/20 0.46
CYP11B1 P15538 2/20 0.45
CYP11B2 P19099 2/20 0.45
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
ENPP2 Q13822 1/20 0.43
MKNK1 Q9BUB5 1/20 0.43
MKNK2 Q9HBH9 1/20 0.43
NOTUM Q6P988 1/20 0.43
CYP2D6 P10635 3/20 0.42
CYP19A1 P11511 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
BAZ2B Q9UIF8 1/20 0.41
MEN1 O00255 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19681491 0.79 CYP3A4 (0.50) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL22601581 0.77 CYP3A4 (0.50) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL19681413 0.75 ENPP2 (0.57) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL270275 0.72 MAPT (0.58) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL31447334 0.72 CYP3A4 (0.47) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL18287244 0.72 CYP3A4 (0.47) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL2693122 0.71 CYP3A4 (0.61) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL9257702 0.70 LMNA (0.39) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL19296052 0.70 CYP3A4 (0.59) CYP3A4CYP2A6CYP11B1CYP11B2LMNA
SCHEMBL25920538 0.70 CYP3A4 (0.51) CYP3A4LMNAMAPTCYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107474071-A Platinum complex, organic light emitting diode and device capable of emitting visible light or near infrared light 季昀 2017-12-15 CN disclosed
US-20170352822-A1 PLATINUM BASED OLED EMITTER SHOWING VISIBLE OR NEAR-INFRARED EMISSION NATIONAL TSING HUA UNIVERSITY (TW) 2017-12-07 US disclosed
US-20170352822-A1 PLATINUM BASED OLED EMITTER SHOWING VISIBLE OR NEAR-INFRARED EMISSION NATIONAL TSING HUA UNIVERSITY (TW) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170352822-A1 PLATINUM BASED OLED EMITTER SHOWING VISIBLE OR NEAR-INFRARED EMISSION OCIAD2, OCIAD1, OPRD1 CYP3A4 1524/4885CYP2A6 1397/4885CYP11B1 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.