SCHEMBL1966752

SCHEMBL1966752

Cc1ccc(N([C]=Cc2ccccc2)c2ccc(C)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.40
RELA Q04206 1/20 0.38
TSHR P16473 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
ACHE P22303 1/20 0.37
ALDH1A1 P00352 5/20 0.37
TRPM8 Q7Z2W7 2/20 0.37
CYP1B1 Q16678 1/20 0.36
HPGD P15428 3/20 0.33
MAPT P10636 2/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
PPARG P37231 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
EGFR P00533 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706592 0.86 RELA (0.35) CYP2C19RELATSHRLMNAALDH1A1
SCHEMBL3983863 0.70 RELA (0.41) RELATSHRLMNAALDH1A1MAPT
SCHEMBL9447282 0.69 CYP2C19 (0.44) CYP2C19RELATSHRLMNAALOX12
SCHEMBL9099736 0.69 ACHE (0.42) TSHRLMNAALOX12ACHEALDH1A1
SCHEMBL4634298 0.69 CA12 (0.44) CYP2C19TSHRLMNAALOX12ACHE
SCHEMBL5618583 0.68 RELA (0.61) RELAALDH1A1TRPM8CYP1B1HPGD
SCHEMBL14003996 0.68 RELA (0.61) RELAALDH1A1TRPM8CYP1B1HPGD
SCHEMBL10434435 0.68 RELA (0.61) RELAALDH1A1TRPM8CYP1B1HPGD
SCHEMBL237049 0.68 RELA (0.61) RELAALDH1A1TRPM8CYP1B1HPGD
SCHEMBL18418097 0.68 RELA (0.61) RELAALDH1A1TRPM8CYP1B1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2351117-A1 RADIATION-EMITTING DEVICE OSRAM Opto Semiconductors GmbH (DE) 2011-08-03 EP disclosed
EP-2335301-A2 RADIATION EMITTING DEVICE OSRAM Opto Semiconductors GmbH (DE) 2011-06-22 EP disclosed
WO-2010048920-A1 RADIATION-EMITTING DEVICE OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2010-05-06 WO disclosed
WO-2010046788-A2 RADIATION EMITTING DEVICE OSRAM OPTO SEMICONDUCTORS GMBH (DE) 2010-04-29 WO disclosed