Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2085046 | 0.89 | CYP2A6 (0.44) | ACHEALDH1A1CYP2A6MAPTKMT2A | |
| SCHEMBL10492226 | 0.84 | APP (0.43) | LMNATSHRALDH1A1CYP2A6MAPT | |
| SCHEMBL339509 | 0.84 | APP (0.43) | LMNATSHRALDH1A1CYP2A6MAPT | |
| SCHEMBL496414 | 0.84 | APP (0.43) | LMNATSHRALDH1A1CYP2A6MAPT | |
| SCHEMBL10535666 | 0.78 | NFE2L2 (0.52) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4660572 | 0.78 | TP53 (0.48) | ACHELMNATSHRALOX12ALDH1A1 | |
| SCHEMBL9490946 | 0.74 | HPGD (0.43) | ALDH1A1CYP1B1MAPTHPGDNPC1 | |
| SCHEMBL9715641 | 0.72 | APP (0.63) | ACHELMNATSHRALOX12ALDH1A1 | |
| SCHEMBL28494872 | 0.71 | TTR (0.37) | ACHELMNATSHRALOX12ALDH1A1 | |
| SCHEMBL5574122 | 0.71 | ALDH1A1 (0.50) | ACHELMNATSHRALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480753-A | DURABILITY | RICOH COMPANY, LTD. (JP) | 1996-01-02 | — | — | US | disclosed |