Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374790 | 0.88 | ALDH1A1 (0.54) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| SCHEMBL29647628 | 0.88 | ALDH1A1 (0.54) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| Hydrochloric Acid SCHEMBL30469303 | 0.86 | ALDH1A1 (0.52) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| Water SCHEMBL28687154 | 0.86 | ALDH1A1 (0.52) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| Hydrochloric Acid SCHEMBL55144 | 0.86 | ALDH1A1 (0.52) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| Hydrochloric Acid SCHEMBL374925 | 0.86 | ALDH1A1 (0.52) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| SCHEMBL10540585 | 0.81 | CYP3A4 (0.74) | CYP3A4TSHRPIK3CAALDH1A1CASP1 | |
| 2-Fluoroethanaminium SCHEMBL4459052 | 0.77 | ALDH1A1 (0.44) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| Sulfuric Acid SCHEMBL9277102 | 0.77 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1CASP1RECQL | |
| SCHEMBL3780784 | 0.76 | MAOA (0.56) | CYP3A4TSHRALDH1A1CASP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348645-A1 | POROUS SUPPORT, COMPOSITE SEMIPERMEABLE MEMBRANE AND SPIRAL WOUND SEPARATION MEMBRANE ELEMENT | NITTO DENKO CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |