SCHEMBL29647628

SCHEMBL29647628

CN(C)c1cccc(N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
TSHR P16473 2/20 0.54
CYP3A4 P08684 4/20 0.52
CASP1 P29466 2/20 0.52
RECQL P46063 1/20 0.52
ALOX15 P16050 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
TP53 P04637 2/20 0.50
MAPK1 P28482 1/20 0.50
SIGMAR1 Q99720 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
HSD17B10 Q99714 1/20 0.41
MAOA P21397 1/20 0.41
NOTUM Q6P988 1/20 0.39
NOS1 P29475 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL374790 1.00 ALDH1A1 (0.54) ALDH1A1TSHRCYP3A4CASP1RECQL
Hydrochloric Acid SCHEMBL374925 0.98 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4CASP1RECQL
Hydrochloric Acid SCHEMBL30469303 0.98 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4CASP1RECQL
Hydrochloric Acid SCHEMBL55144 0.98 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4CASP1RECQL
Water SCHEMBL28687154 0.98 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4CASP1RECQL
2-Fluoroethanaminium SCHEMBL4459052 0.88 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4CASP1RECQL
Sulfuric Acid SCHEMBL9277102 0.88 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4CASP1RECQL
SCHEMBL19667909 0.88 CYP3A4 (0.54) ALDH1A1TSHRCYP3A4CASP1RECQL
SCHEMBL3780784 0.87 MAOA (0.56) ALDH1A1TSHRCYP3A4CASP1RECQL
SCHEMBL11503532 0.85 CYP3A4 (0.52) ALDH1A1TSHRCYP3A4CASP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638695-A Phenanthroline-substituted methyl guanidine compound, and preparation and application thereof 上海健康医学院 2025-03-18 CN disclosed
CN-115201304-B Preparation method and application of CuNPs-5-Br-PADMA/ITO electrode 西安文理学院 2024-03-01 CN disclosed
CN-115201304-A Preparation method and application of CuNPs-5-Br-PADMA/ITO electrode 西安文理学院 2022-10-18 CN disclosed
CN-110845457-B Usnic acid derivative, preparation method thereof and application of usnic acid derivative in Alzheimer disease medicine 中国药科大学 2022-06-10 CN disclosed