Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20033792 | 0.78 | MGAM (0.41) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL5399972 | 0.77 | CYP2C9 (0.37) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL16796694 | 0.76 | PTGS2 (0.36) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL16477715 | 0.75 | MMP8 (0.54) | CYP1A2CYP3A4GABRA1GABRB2CYP2C9 | |
| SCHEMBL13751893 | 0.75 | MMP8 (0.54) | CYP1A2CYP3A4GABRA1GABRB2CYP2C9 | |
| SCHEMBL20033794 | 0.75 | ALDH1A1 (0.38) | CYP1A2CYP3A4GABRA1GABRB2CYP11B1 | |
| SCHEMBL5325939 | 0.74 | ESR1 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL6981185 | 0.73 | ALDH1A1 (0.40) | CYP2C9CYP2C19LMNASIRT2ALDH1A1 | |
| SCHEMBL20154360 | 0.73 | ALDH1A1 (0.40) | CYP2C9CYP2C19LMNASIRT2ALDH1A1 | |
| SCHEMBL20564825 | 0.72 | KMT2A (0.45) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834535-B2 | Sulfamate derivative compounds for use in treating or alleviating pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2017-12-05 | — | — | US | disclosed |