Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092683 | 0.79 | PGR (0.52) | PARGKMT2ATSHRRORCSMN1; SMN2 | |
| SCHEMBL17434328 | 0.78 | PARG (0.50) | PARGKMT2ATSHRRORCSMN1; SMN2 | |
| SCHEMBL17434453 | 0.78 | ALDH1A1 (0.68) | PARGKMT2ATSHRSMN1; SMN2KDM4E | |
| SCHEMBL17434513 | 0.78 | PARG (0.50) | PARGKMT2ATSHRSMN1; SMN2KDM4E | |
| SCHEMBL17433946 | 0.77 | RORC (0.51) | PARGKMT2ATSHRRORCSMN1; SMN2 | |
| SCHEMBL17433948 | 0.77 | RORC (0.51) | PARGKMT2ATSHRRORCSMN1; SMN2 | |
| SCHEMBL17434593 | 0.76 | RORC (0.64) | KMT2ARORCSMN1; SMN2KDM4EMAPT | |
| SCHEMBL17434391 | 0.76 | RORC (0.54) | PARGKMT2ATSHRRORCSMN1; SMN2 | |
| SCHEMBL25431460 | 0.75 | PARG (0.48) | PARGKMT2ATSHRRORCSMN1; SMN2 | |
| SCHEMBL17434508 | 0.75 | RORC (0.69) | KMT2ARORCSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-05 | — | — | US | disclosed |