Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669889 | 0.81 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL15600844 | 0.79 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL19669893 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL19104254 | 0.74 | KDM4C (0.31) | — | |
| SCHEMBL18133908 | 0.74 | EPHX1 (0.31) | — | |
| SCHEMBL7641975 | 0.72 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL13926370 | 0.72 | DGAT1 (0.32) | — | |
| SCHEMBL31586775 | 0.71 | — | — | |
| SCHEMBL19669891 | 0.69 | CHRM1 (0.41) | ALDH1A1 | |
| SCHEMBL19669913 | 0.68 | SMN1; SMN2 (0.39) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834571-B2 | Compounds for inhibiting cell proliferation in EGFR-driven cancers | ARIAD PHARMACEUTICALS, INC. (US) | 2017-12-05 | — | — | US | disclosed |