Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22023572 | 0.91 | GPR174 (0.40) | ELANEGPR174KMT2AMEN1ALDH1A1 | |
| SCHEMBL20112832 | 0.91 | MAPT (0.42) | ELANEGPR174KMT2AMEN1ALDH1A1 | |
| SCHEMBL18509891 | 0.90 | GPR174 (0.40) | ELANEGPR174KMT2AMEN1ALDH1A1 | |
| SCHEMBL18522596 | 0.89 | KMT2A (0.38) | GPR174KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL9607783 | 0.89 | ELANE (0.49) | ELANEKMT2AALDH1A1POLBATM | |
| SCHEMBL20365886 | 0.88 | ELANE (0.36) | ELANEGPR174KMT2AMEN1ALDH1A1 | |
| SCHEMBL11238246 | 0.87 | KMT2A (0.45) | GPR174KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL20112831 | 0.85 | MAPT (0.42) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL19670076 | 0.84 | ELANE (0.45) | ELANEGPR174KMT2AMEN1ALDH1A1 | |
| SCHEMBL18646588 | 0.84 | FFAR1 (0.40) | KMT2AMEN1MAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489329-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-12 | — | — | EP | disclosed |
| EP-3353261-B1 | METHOD OF CONTROLLING THE PRETILT ANGLE IN POLYMER STABILISED LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2020-05-27 | — | — | EP | disclosed |
| US-20180119010-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-03 | — | — | US | disclosed |