Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 17/20 | 0.47 |
| ▸ | HTR2A | P28223 | 15/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670620 | 0.92 | HTR2A (0.38) | HTR2CHTR2A | |
| SCHEMBL19706092 | 0.89 | CYP11B2 (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL19365719 | 0.89 | HTR2C (0.52) | HTR2CHTR2AHTR2B | |
| SCHEMBL19670565 | 0.89 | WNT3A (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL19670124 | 0.87 | WNT3A (0.40) | — | |
| SCHEMBL19670622 | 0.87 | CSF1R (0.40) | — | |
| SCHEMBL1815620 | 0.87 | HTR2C (0.49) | HTR2CHTR2A | |
| SCHEMBL19670532 | 0.85 | FAAH (0.41) | — | |
| SCHEMBL19670591 | 0.85 | FGFR4 (0.42) | — | |
| SCHEMBL19865050 | 0.85 | HTR2C (0.40) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |