Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 17/20 | 0.51 |
| ▸ | HTR2A | P28223 | 12/20 | 0.51 |
| ▸ | HTR2B | P41595 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20632292 | 0.90 | HTR2C (0.41) | HTR2CHTR2AHTR2BCYP1A2MEN1 | |
| SCHEMBL20631979 | 0.87 | CYP11B2 (0.41) | HTR2CHTR2AHTR2BCYP1A2CYP3A4 | |
| SCHEMBL16776130 | 0.84 | HTR2C (0.48) | HTR2CHTR2AHTR2BCYP1A2MEN1 | |
| SCHEMBL19365719 | 0.82 | HTR2C (0.52) | HTR2CHTR2AHTR2BCYP1A2MEN1 | |
| SCHEMBL19670524 | 0.80 | CYP11B2 (0.39) | HTR2CHTR2AHTR2BCYP1A2 | |
| SCHEMBL19670473 | 0.79 | HTR2C (0.51) | HTR2CHTR2AHTR2BCYP1A2MEN1 | |
| SCHEMBL19669976 | 0.79 | HTR2A (0.52) | HTR2CHTR2AHTR2BCYP1A2MEN1 | |
| SCHEMBL19670295 | 0.79 | HTR2C (0.39) | HTR2CHTR2AHTR2B | |
| SCHEMBL19365498 | 0.79 | HTR2C (0.46) | HTR2CHTR2AHTR2BCYP1A2MEN1 | |
| SCHEMBL19365528 | 0.78 | NAMPT (0.47) | HTR2CHTR2AHTR2BCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |